What is Leucine?

I’ve spoken to hundreds of people about the benefits of Leucine in the Shaklee 180 products.  Here is a more detailed explanation of why leucine is so important for long-term, sustainable weight loss and increased metabolism.  You can also find out how to use Leucine here:  http://bit.ly/1yu9ndn

“Being overweight or obese is the number one health issue of our day. Excess weight is associated with many diseases, including diabetes, hypertension, high cholesterol, coronary heart disease, stroke, sleep apnea, and osteoarthritis. Excess weight increases suffering, decreases quality of living, reduces life expectancy, and places a large burden on already burdened health care resources.1

Leucine breakdownReversing the obesity epidemic will no doubt require advances on many fronts, including public health policy, consumer and physician education, and community engagement in supporting initiatives to help people become more active. There are literally hundreds of weight-loss programs, most of which do indeed lead to weight loss—but no attention is paid to what constitutes healthy and sustainable weight loss. Loss of water weight or muscle mass (as occurs in all programs) initially looks good on the scale, but fails in the long term to achieve the goal of permanent weight loss.

Since lean muscle mass constitutes the majority of metabolism2, loss of muscle mass is unsustainable in the long-term as metabolism will plummet along with weight loss, which leads to regaining of weight unless permanent changes in diet and lifestyle have occurred. Maintenance of lean muscle mass, therefore, is a key element of a successful weight-loss program.3

Protein maintains muscle mass

Since the time of the Roman Empire, protein has been known to help build muscles. When amino acids (the building blocks of proteins) were discovered, it was clear that only certain types of amino acids led to muscle building. The branched-chain amino acids (leucine, isoleucine, and valine) were found to have the most effect on maintaining muscle mass, and eventually leucine emerged as the amino acid that has unique effects on protein synthesis.4

Leucine has been shown to have the following effects helpful for weight loss:

  • Leucine inhibits the breakdown of other proteins.5
  • Leucine increases metabolism (thermogenic effect).6
  • During a low-calorie diet, consumption of leucine helps maintain lean muscle mass so that weight loss can preferentially come from fat stores.7
  • Leucine stimulates a rise in plasma leptin and helps people feel full.8

Several long-term studies in obese participants who consumed a high-soy protein/low-fat diet suggested improved body composition by losing fat and preserving muscle mass.9 Leucine supplementation combined with exercise appears to be one of the most effective way for maintaining lean muscle mass for weight loss.10

Conclusion

Excess weight continues to be a challenging public health problem. It is clear that increased protein content of meals during a weight-loss program not only increases satiety and modulates cravings, but also is the main metabolic messenger for the synthesis and maintenance of lean muscle mass.

The majority of leucine-related literature confirms the significance of leucine as a dietary modulator of muscle maintenance that is useful for weight loss and maintenance. The leucine content of a meal may be the critical factor for determining the quantity and quality of proteins necessary at a meal for stimulation of muscle protein synthesis and/or decreased muscle breakdown, and the maintenance of lean body mass and metabolism.”

 

Read directly from article source here:  http://member.myshaklee.com/us/en/article/15-005-Jan-HS_Leucine-8e36ec168cc04f6d494d61097be4ea6e?campaign_id=mrkt_hs:jan_hs_email:jan_01222014:link_ThePowerofProtein&sp_mid=11563279&sp_rid=ZXZhcnVtYmxlQGNhcm9saW5hLnJyLmNvbQS2


  1. Wolf AM, Colditz GA. Current estimates of the economic cost of obesity in the United States. Obes Res. 1998 Mar;6(2):97-106. PMID: 9545015.
  2. Zurlo F, Larson K, Bogardus C, Ravussin E. Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest. 1990 Nov;86(5):1423-7. PMID: 2243122.
  3. Deibert P, König D, Schmidt-Trucksaess A, et al. Weight loss without losing muscle mass in pre-obese and obese subjects induced by a high-soy-protein diet. Int J Obes Relat Metab Disord. 2004 Oct;28(10):1349-52. PMID: 15303108.
  4. Layman DK, Walker DA. Potential importance of leucine in treatment of obesity and the metabolic syndrome. J Nutr. 2006 Jan;136(1 Suppl):319S-23S. PMID: 16365106. PDF
  5. Zanchi NE, Nicastro H, Lancha AH Jr. Potential antiproteolytic effects of L-leucine: observations of in vitro and in vivo studies. Nutr Metab (Lond). 2008 Jul 17;5:20. doi: 10.1186/1743-7075-5-20. PMID: 18637185. PDF
  6. Tappy L, Jéquier E, Acheson K. Thermic effect of infused amino acids in healthy humans and in subjects with insulin resistance. Am J Clin Nutr. 1993 Jun;57(6):912-6. PMID: 8503362.
  7. Churchward-Venne TA, Breen L, et al. Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial. Am J Clin Nutr. 2014 Feb;99(2):276-86. PMID: 24284442.
  8. Lynch CJ, Gern B, Lloyd C, Hutson SM, Eicher R, Vary TC. Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E621-30. Epub 2006 Apr 25. PMID: 16638821. PDF
  9. Deibert P, König D, Schmidt-Trucksaess A, et al. Weight loss without losing muscle mass in pre-obese and obese subjects induced by a high-soy-protein diet. Int J Obes Relat Metab Disord. 2004 Oct;28(10):1349-52. PMID: 15303108.
  10. Westcott W, Varghese J, DiNubile N, et al. Exercise and Nutrition More Effective than Exercise Alone for Increasing Lean Weight and Reducing Resting Blood Pressure. Journal of Exercise Physiology Online. 2011, 14(4). PDF

 

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